Immunization with PspA incorporated into a poly(ethylene oxide) matrix elicits protective immunity against Streptococcus pneumoniae.
نویسندگان
چکیده
CBA/N mice were immunized with PspA in a poly(ethylene oxide) matrix to examine its ability to deliver the antigen and modulate the immune response. All mice receiving PspA in the matrix survived a lethal pneumococcal challenge and had serum anti-PspA antibody levels statistically higher than mice receiving PspA alone (P < 0.009).
منابع مشابه
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ورودعنوان ژورنال:
- Clinical and vaccine immunology : CVI
دوره 14 6 شماره
صفحات -
تاریخ انتشار 2007